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Iron accumulation in tumor-associated macrophages marks an improved overall survival in patients with lung adenocarcinoma
Iron-loaded tumor-associated macrophages (iTAMs) show a pro-inflammatory phenotype, hallmarked by anti-tumorigenic activity and an ability to attenuate tumor growth. Here we explored the relevance of these findings in lung cancer patients by investigating the impact of the iTAM content in the tumor...
Autores principales: | Thielmann, Carl Maximilian, Costa da Silva, Milene, Muley, Thomas, Meister, Michael, Herpel, Esther, Muckenthaler, Martina U. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683135/ https://www.ncbi.nlm.nih.gov/pubmed/31383898 http://dx.doi.org/10.1038/s41598-019-47833-x |
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