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Cigarette smoke activates the parthanatos pathway of cell death in human bronchial epithelial cells
Tobacco smoke negatively affects human bronchial epithelial (HBE) cells and is directly implicated in the etiology of smoking related respiratory diseases. Smoke exposure causes double-stranded DNA breaks and DNA damage activates PARP-1, the key mediator of the parthanatos pathway of cell death. We...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683143/ https://www.ncbi.nlm.nih.gov/pubmed/31396404 http://dx.doi.org/10.1038/s41420-019-0205-3 |