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Cigarette smoke activates the parthanatos pathway of cell death in human bronchial epithelial cells

Tobacco smoke negatively affects human bronchial epithelial (HBE) cells and is directly implicated in the etiology of smoking related respiratory diseases. Smoke exposure causes double-stranded DNA breaks and DNA damage activates PARP-1, the key mediator of the parthanatos pathway of cell death. We...

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Detalles Bibliográficos
Autores principales:	Künzi, Lisa, Holt, Gregory E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683143/ https://www.ncbi.nlm.nih.gov/pubmed/31396404 http://dx.doi.org/10.1038/s41420-019-0205-3

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