miR-425 deficiency promotes necroptosis and dopaminergic neurodegeneration in Parkinson’s disease

A major hallmark of Parkinson’s disease (PD) is the degeneration of dopaminergic neurons in the substantia nigra, and the causative mechanism is thought to be the activation of programmed neuronal death. Necroptosis is a regulated process of cell death triggered by RIPK1. Although the pathophysiolog...

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Detalles Bibliográficos
Autores principales: Hu, Yong-Bo, Zhang, Yong-Fang, Wang, Hao, Ren, Ru-Jing, Cui, Hai-Lun, Huang, Wan-Ying, Cheng, Qi, Chen, Hong-Zhuan, Wang, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683159/
https://www.ncbi.nlm.nih.gov/pubmed/31383850
http://dx.doi.org/10.1038/s41419-019-1809-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683159/
https://www.ncbi.nlm.nih.gov/pubmed/31383850
http://dx.doi.org/10.1038/s41419-019-1809-5

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