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The interleukin-33-mediated inhibition of expression of two key genes implicated in atherosclerosis in human macrophages requires MAP kinase, phosphoinositide 3-kinase and nuclear factor-κB signaling pathways

Atherosclerosis, a chronic inflammatory disorder of the walls of arteries, causes more deaths worldwide than any other disease. Cytokines, which are present at high levels in atherosclerotic plaques, play important roles in regulating the initiation and the progression of the disease. Previous studi...

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Detalles Bibliográficos
Autores principales: Buckley, Melanie L., Williams, Jessica O., Chan, Yee-Hung, Laubertová, Lucia, Gallagher, Hayley, Moss, Joe W. E., Ramji, Dipak P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683160/
https://www.ncbi.nlm.nih.gov/pubmed/31383884
http://dx.doi.org/10.1038/s41598-019-47620-8