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Colorectal cancer cells respond differentially to autophagy inhibition in vivo

Autophagy has both tumor-promoting and -suppressing effects in cancer, including colorectal cancer (CRC), with transformed cells often exhibiting high autophagic flux. In established tumors, autophagy inhibition can lead to opposite responses resulting in either tumor cell death or hyperproliferatio...

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Detalles Bibliográficos
Autores principales: Lauzier, Annie, Normandeau-Guimond, Josiann, Vaillancourt-Lavigueur, Vanessa, Boivin, Vincent, Charbonneau, Martine, Rivard, Nathalie, Scott, Michelle S., Dubois, Claire M., Jean, Steve
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683171/
https://www.ncbi.nlm.nih.gov/pubmed/31383875
http://dx.doi.org/10.1038/s41598-019-47659-7