Synaptotagmin-1 enables frequency coding by suppressing asynchronous release in a temperature dependent manner

To support frequency-coded information transfer, mammalian synapses tightly synchronize neurotransmitter release to action potentials (APs). However, release desynchronizes during AP trains, especially at room temperature. Here we show that suppression of asynchronous release by Synaptotagmin-1 (Syt...

Descripción completa

Detalles Bibliográficos
Autores principales: Huson, Vincent, van Boven, Maaike A., Stuefer, Alexia, Verhage, Matthijs, Cornelisse, L. Niels
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683208/
https://www.ncbi.nlm.nih.gov/pubmed/31383906
http://dx.doi.org/10.1038/s41598-019-47487-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683208/
https://www.ncbi.nlm.nih.gov/pubmed/31383906
http://dx.doi.org/10.1038/s41598-019-47487-9

Ejemplares similares