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A Decoy-Receptor Approach Using Nicotinic Acetylcholine Receptor Mimics Reveals Their Potential as Novel Therapeutics Against Neurotoxic Snakebite

Snakebite is a neglected tropical disease that causes 138,000 deaths each year. Neurotoxic snake venoms contain small neurotoxins, including three-finger toxins (3FTxs), which can cause rapid paralysis in snakebite victims by blocking postsynaptic transmission via nicotinic acetylcholine receptors (...

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Detalles Bibliográficos
Autores principales:	Albulescu, Laura-Oana, Kazandjian, Taline, Slagboom, Julien, Bruyneel, Ben, Ainsworth, Stuart, Alsolaiss, Jaffer, Wagstaff, Simon C., Whiteley, Gareth, Harrison, Robert A., Ulens, Chris, Kool, Jeroen, Casewell, Nicholas R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683245/ https://www.ncbi.nlm.nih.gov/pubmed/31417406 http://dx.doi.org/10.3389/fphar.2019.00848

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