Niclosamide reverses adipocyte induced epithelial-mesenchymal transition in breast cancer cells via suppression of the interleukin-6/STAT3 signalling axis

The microenvironment of breast cancer comprises predominantly of adipocytes. Adipocytes drive cancer progression through the secretion adipocytokines. Adipocytes induce epithelial mesenchymal transition of breast cancer cells through paracrine IL-6/Stat3 signalling. Treatment approaches that can tar...

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Detalles Bibliográficos
Autores principales: Gyamfi, Jones, Lee, Yun-Hee, Min, Byung Soh, Choi, Junjeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683291/
https://www.ncbi.nlm.nih.gov/pubmed/31383893
http://dx.doi.org/10.1038/s41598-019-47707-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683291/
https://www.ncbi.nlm.nih.gov/pubmed/31383893
http://dx.doi.org/10.1038/s41598-019-47707-2

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