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Vasculogenic mimicry is associated with trastuzumab resistance of HER2-positive breast cancer
BACKGROUND: Trastuzumab is a drug that targets the receptor tyrosine kinase HER2 and is essential for the treatment of HER2-positive breast cancer. Resistance to the drug leads to severe consequences, including disease recurrence, tumor enlargement, and metastasis. We hypothesized that trastuzumab t...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683360/ https://www.ncbi.nlm.nih.gov/pubmed/31387614 http://dx.doi.org/10.1186/s13058-019-1167-3 |