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Behavioral and steroidogenic pharmacology of phenyl ring substituted etomidate analogs in rats

BACKGROUND: Cushing’s syndrome is an endocrine disorder characterized by the overproduction of adrenocortical steroids. Steroidogenesis enzyme inhibitors are the mainstays of pharmacological treatment. Unfortunately, they produce significant side effects. Among the most potent inhibitors is the gene...

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Detalles Bibliográficos
Autores principales: McGrath, Megan, Hofmann, Alissa, Raines, Douglas E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683373/
https://www.ncbi.nlm.nih.gov/pubmed/31383012
http://dx.doi.org/10.1186/s40360-019-0328-4