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PLCε regulates prostate cancer mitochondrial oxidative metabolism and migration via upregulation of Twist1
BACKGROUND: Metabolic rewiring is a common feature of many cancer types, including prostate cancer (PCa). Alterations in master genes lead to mitochondrial metabolic rewiring and provide an appealing target to inhibit cancer progression and improve survival. Phospholipase C (PLC)ε is a regulator of...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683382/ https://www.ncbi.nlm.nih.gov/pubmed/31383001 http://dx.doi.org/10.1186/s13046-019-1323-8 |