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PLCε regulates prostate cancer mitochondrial oxidative metabolism and migration via upregulation of Twist1

BACKGROUND: Metabolic rewiring is a common feature of many cancer types, including prostate cancer (PCa). Alterations in master genes lead to mitochondrial metabolic rewiring and provide an appealing target to inhibit cancer progression and improve survival. Phospholipase C (PLC)ε is a regulator of...

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Detalles Bibliográficos
Autores principales:	Fan, Jiaxin, Fan, Yanru, Wang, Xiao, Niu, Lingfang, Duan, Limei, Yang, Jinxiao, Li, Luo, Gao, Yingying, Wu, Xiaohou, Luo, Chunli
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683382/ https://www.ncbi.nlm.nih.gov/pubmed/31383001 http://dx.doi.org/10.1186/s13046-019-1323-8

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