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Characterisation of DNA methylation changes in EBF3 and TBC1D16 associated with tumour progression and metastasis in multiple cancer types

BACKGROUND: Characteristic DNA methylation differences have been identified between primary and metastatic melanomas at EBF3 and/or TBC1D16 gene loci. To further evaluate whether these epigenetic changes may act more generally as drivers of tumour onset and metastasis, we have investigated DNA methy...

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Detalles Bibliográficos
Autores principales: Rodger, Euan J., Chatterjee, Aniruddha, Stockwell, Peter A., Eccles, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683458/
https://www.ncbi.nlm.nih.gov/pubmed/31383000
http://dx.doi.org/10.1186/s13148-019-0710-5