Local and abscopal responses in advanced intrahepatic cholangiocarcinoma with low TMB, MSS, pMMR and negative PD-L1 expression following combined therapy of SBRT with PD-1 blockade

BACKGROUND: Late-stage or recurrent intrahepatic cholangiocarcinoma (ICC) patients exhibit poor prognosis due to limited sensitivity to chemotherapy or radiotherapy and coexistence of multiple lesions. Programmed cell death protein 1 (PD-1) blockade provides a therapeutic opportunity for patients wi...

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Detalles Bibliográficos
Autores principales: Liu, Xiaoliang, Yao, Jianfei, Song, Lele, Zhang, Sujing, Huang, Tanxiao, Li, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683483/
https://www.ncbi.nlm.nih.gov/pubmed/31383016
http://dx.doi.org/10.1186/s40425-019-0692-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683483/
https://www.ncbi.nlm.nih.gov/pubmed/31383016
http://dx.doi.org/10.1186/s40425-019-0692-z

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