Depletion of regulatory T cells increases T cell brain infiltration, reactive astrogliosis, and interferon-γ gene expression in acute experimental traumatic brain injury

BACKGROUND: Traumatic brain injury (TBI) is a major cause of death and disability. T cells were shown to infiltrate the brain during the first days after injury and to exacerbate tissue damage. The objective of this study was to investigate the hitherto unresolved role of immunosuppressive, regulato...

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Detalles Bibliográficos
Autores principales: Krämer, Tobias J., Hack, Nathalia, Brühl, Till J., Menzel, Lutz, Hummel, Regina, Griemert, Eva-Verena, Klein, Matthias, Thal, Serge C., Bopp, Tobias, Schäfer, Michael K. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683516/
https://www.ncbi.nlm.nih.gov/pubmed/31383034
http://dx.doi.org/10.1186/s12974-019-1550-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683516/
https://www.ncbi.nlm.nih.gov/pubmed/31383034
http://dx.doi.org/10.1186/s12974-019-1550-0

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