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BMP2 secretion from hepatocellular carcinoma cell HepG2 enhances angiogenesis and tumor growth in endothelial cells via activation of the MAPK/p38 signaling pathway

BACKGROUND: Hepatocellular carcinoma (HCC) is one of the most common tumors globally, with varying prevalence based on endemic risk factors. Bone morphogenetic protein (BMP) exhibits a broad spectrum of biological activities in various tissues including angiogenesis. Here, this study aimed to invest...

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Detalles Bibliográficos
Autores principales: Feng, Peng-Cheng, Ke, Xing-Fei, Kuang, Hui-Lan, Pan, Li-Li, Ye, Qiang, Wu, Jian-Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683571/
https://www.ncbi.nlm.nih.gov/pubmed/31387619
http://dx.doi.org/10.1186/s13287-019-1301-2