Regulation of heart rate and the pacemaker current by phosphoinositide 3-kinase signaling

Heart rate in physiological conditions is set by the sinoatrial node (SN), the primary cardiac pacing tissue. Phosphoinositide 3-kinase (PI3K) signaling is a major regulatory pathway in all normal cells, and its dysregulation is prominent in diabetes, cancer, and heart failure. Here, we show that in...

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Detalles Bibliográficos
Autores principales: Lin, Richard Z., Lu, Zhongju, Anyukhovsky, Evgeny P., Jiang, Ya-Ping, Wang, Hong Zhan, Gao, Junyuan, Rosen, Michael R., Ballou, Lisa M., Cohen, Ira S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683667/
https://www.ncbi.nlm.nih.gov/pubmed/31217223
http://dx.doi.org/10.1085/jgp.201812293

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683667/
https://www.ncbi.nlm.nih.gov/pubmed/31217223
http://dx.doi.org/10.1085/jgp.201812293

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