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Beyond proteases: Basement membrane mechanics and cancer invasion

In epithelial cancers, cells must invade through basement membranes (BMs) to metastasize. The BM, a thin layer of extracellular matrix underlying epithelial and endothelial tissues, is primarily composed of laminin and collagen IV and serves as a structural barrier to cancer cell invasion, intravasa...

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Detalles Bibliográficos
Autores principales: Chang, Julie, Chaudhuri, Ovijit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683740/
https://www.ncbi.nlm.nih.gov/pubmed/31315943
http://dx.doi.org/10.1083/jcb.201903066