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Synaptic neurexin-1 assembles into dynamically regulated active zone nanoclusters

Neurexins are well-characterized presynaptic cell adhesion molecules that engage multifarious postsynaptic ligands and organize diverse synapse properties. However, the precise synaptic localization of neurexins remains enigmatic. Using super-resolution microscopy, we demonstrate that neurexin-1 for...

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Detalles Bibliográficos
Autores principales: Trotter, Justin H., Hao, Junjie, Maxeiner, Stephan, Tsetsenis, Theodoros, Liu, Zhihui, Zhuang, Xiaowei, Südhof, Thomas C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683742/
https://www.ncbi.nlm.nih.gov/pubmed/31262725
http://dx.doi.org/10.1083/jcb.201812076