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MicroRNA-145-5p promotes asthma pathogenesis by inhibiting kinesin family member 3A expression in mouse airway epithelial cells

BACKGROUND: MicroRNA (miR)-145-5p is a respiratory disease biomarker, and is upregulated in asthma pathogenesis. However, its underlying mechanisms were unclear, so were investigated in the present study. METHODS: A mouse model of asthma was established by challenge with house dust mite (HDM) extrac...

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Detalles Bibliográficos
Autores principales: Xiong, Tao, Du, Ying, Fu, Zhou, Geng, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683905/
https://www.ncbi.nlm.nih.gov/pubmed/31264490
http://dx.doi.org/10.1177/0300060518789819