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E-protein–regulated expression of CXCR4 adheres preselection thymocytes to the thymic cortex

Preselection thymocytes are normally retained in the thymic cortex, but the mechanisms responsible remain incompletely understood. We now report that deletion of genes encoding the E-protein transcription factors E2A and HEB disorders chemokine receptor expression on developing thymocytes to allow e...

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Detalles Bibliográficos
Autores principales: Kadakia, Tejas, Tai, Xuguang, Kruhlak, Michael, Wisniewski, Jan, Hwang, Il-Young, Roy, Sumedha, Guinter, Terry I., Alag, Amala, Kehrl, John H., Zhuang, Yuan, Singer, Alfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683992/
https://www.ncbi.nlm.nih.gov/pubmed/31201207
http://dx.doi.org/10.1084/jem.20182285