C3- and CR3-dependent microglial clearance protects photoreceptors in retinitis pigmentosa

Complement activation has been implicated as contributing to neurodegeneration in retinal and brain pathologies, but its role in retinitis pigmentosa (RP), an inherited and largely incurable photoreceptor degenerative disease, is unclear. We found that multiple complement components were markedly up...

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Detalles Bibliográficos
Autores principales: Silverman, Sean M., Ma, Wenxin, Wang, Xu, Zhao, Lian, Wong, Wai T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683998/
https://www.ncbi.nlm.nih.gov/pubmed/31209071
http://dx.doi.org/10.1084/jem.20190009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683998/
https://www.ncbi.nlm.nih.gov/pubmed/31209071
http://dx.doi.org/10.1084/jem.20190009

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