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Cannabinoid receptor-1 antagonism: a new perspective on treating a murine schistosomal liver fibrosis model

BACKGROUND: Formation of schistosomal granulomata surrounding the ova can result in schistosomiasis-associated liver fibrosis (SSLF). The current standard of treatment is praziquantel (PZQ), which cannot effectively reverse SSLF. The role of the cannabinoid (CB) receptor family in liver fibrosis has...

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Detalles Bibliográficos
Autores principales: Issa, Yasmine Amr, El Achy, Samar Nabil, Mady, Rasha Fadly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Oswaldo Cruz, Ministério da Saúde 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684006/
https://www.ncbi.nlm.nih.gov/pubmed/31389521
http://dx.doi.org/10.1590/0074-02760190062