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Inhibitory effect of nintedanib on VEGF secretion in retinal pigment epithelial cells induced by exposure to a necrotic cell lysate

Necrosis is a form of cell death that results in rupture of the plasma membrane and the release of cellular contents, and it can give rise to sterile inflammation in the retina and other tissues. The secretion of vascular endothelial growth factor (VEGF) by retinal pigment epithelial (RPE) cells con...

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Detalles Bibliográficos
Autores principales: Hatano, Makoto, Tokuda, Kazuhiro, Kobayashi, Yuka, Yamashiro, Chiemi, Uchi, Sho-Hei, Kobayashi, Masaaki, Kimura, Kazuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684070/
https://www.ncbi.nlm.nih.gov/pubmed/31386668
http://dx.doi.org/10.1371/journal.pone.0218632