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Functionalization of CD36 cardiovascular disease and expression associated variants by interdisciplinary high throughput analysis

CD36 is a platelet membrane glycoprotein whose engagement with oxidized low-density lipoprotein (oxLDL) results in platelet activation. The CD36 gene has been associated with platelet count, platelet volume, as well as lipid levels and CVD risk by genome-wide association studies. Platelet CD36 expre...

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Detalles Bibliográficos
Autores principales: Madan, Namrata, Ghazi, Andrew R., Kong, Xianguo, Chen, Edward S., Shaw, Chad A., Edelstein, Leonard C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684090/
https://www.ncbi.nlm.nih.gov/pubmed/31344026
http://dx.doi.org/10.1371/journal.pgen.1008287