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Functionalization of CD36 cardiovascular disease and expression associated variants by interdisciplinary high throughput analysis
CD36 is a platelet membrane glycoprotein whose engagement with oxidized low-density lipoprotein (oxLDL) results in platelet activation. The CD36 gene has been associated with platelet count, platelet volume, as well as lipid levels and CVD risk by genome-wide association studies. Platelet CD36 expre...
Autores principales: | Madan, Namrata, Ghazi, Andrew R., Kong, Xianguo, Chen, Edward S., Shaw, Chad A., Edelstein, Leonard C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684090/ https://www.ncbi.nlm.nih.gov/pubmed/31344026 http://dx.doi.org/10.1371/journal.pgen.1008287 |
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