The origins and relatedness structure of mixed infections vary with local prevalence of P. falciparum malaria

Individual malaria infections can carry multiple strains of Plasmodium falciparum with varying levels of relatedness. Yet, how local epidemiology affects the properties of such mixed infections remains unclear. Here, we develop an enhanced method for strain deconvolution from genome sequencing data,...

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Detalles Bibliográficos
Autores principales: Zhu, Sha Joe, Hendry, Jason A, Almagro-Garcia, Jacob, Pearson, Richard D, Amato, Roberto, Miles, Alistair, Weiss, Daniel J, Lucas, Tim CD, Nguyen, Michele, Gething, Peter W, Kwiatkowski, Dominic, McVean, Gil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Epidemiology and Global Health
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684230/
https://www.ncbi.nlm.nih.gov/pubmed/31298657
http://dx.doi.org/10.7554/eLife.40845

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684230/
https://www.ncbi.nlm.nih.gov/pubmed/31298657
http://dx.doi.org/10.7554/eLife.40845

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