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Structure of the full-length Clostridium difficile toxin B

Clostridium difficile is an opportunistic pathogen that establishes in the colon when the gut microbiota is disrupted by antibiotics or disease. C. difficile infection (CDI) is largely caused by two virulence factors TcdA and TcdB. Here, we report a 3.87 Å resolution crystal structure of TcdB holoto...

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Detalles Bibliográficos
Autores principales: Chen, Peng, Lam, Kwok-ho, Liu, Zheng, Mindlin, Frank A., Chen, Baohua, Gutierrez, Craig B., Huang, Lan, Zhang, Yongrong, Hamza, Therwa, Feng, Hanping, Matsui, Tsutomu, Bowen, Mark E., Perry, Kay, Jin, Rongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684407/
https://www.ncbi.nlm.nih.gov/pubmed/31308519
http://dx.doi.org/10.1038/s41594-019-0268-0