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Asymmetric histone inheritance via strand-specific incorporation and biased replication fork movement

Many stem cells undergo asymmetric division to produce a self-renewing stem cell and a differentiating daughter cell. Here we show that, similarly to H3, histone H4 is inherited asymmetrically in Drosophila melanogaster male germline stem cells undergoing asymmetric division. In contrast, both H2A a...

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Detalles Bibliográficos
Autores principales: Wooten, Matthew, Snedeker, Jonathan, Nizami, Zehra F., Yang, Xinxing, Ranjan, Rajesh, Urban, Elizabeth, Kim, Jee Min, Gall, Joseph, Xiao, Jie, Chen, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684448/
https://www.ncbi.nlm.nih.gov/pubmed/31358945
http://dx.doi.org/10.1038/s41594-019-0269-z