A model to study the inhibition of nsP2B-nsP3 protease of dengue virus with imidazole, oxazole, triazole thiadiazole, and thiazolidine based scaffolds

A theoretical model was developed to allosterically inhibit the biological activity of dengue virus (DENV) by targeting the non-structural protein ns2B-nsP3 protease based on the in silico studies. The imidazole, oxazole, triazole, thiadiazole, and thiazolidine based scaffolds were imported from the...

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Detalles Bibliográficos
Autores principales: Vishvakarma, Vijay Kumar, Shukla, Nidhi, Reetu, Kumari, Kamlesh, Patel, Rajan, Singh, Prashant
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684460/
https://www.ncbi.nlm.nih.gov/pubmed/31406937
http://dx.doi.org/10.1016/j.heliyon.2019.e02124

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684460/
https://www.ncbi.nlm.nih.gov/pubmed/31406937
http://dx.doi.org/10.1016/j.heliyon.2019.e02124

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