Aminomethyl spectinomycins: a novel antibacterial chemotype for biothreat pathogens

New antibiotics that are active against multi-drug-resistant strains and difficult-to-treat bacterial infections are needed. Synthetic modification of spectinomycin, a bacterial protein synthesis inhibitor, has been shown to increase antibacterial activity compared with spectinomycin. Aminomethyl sp...

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Detalles Bibliográficos
Autores principales: Scarff, Jennifer M., Waidyarachchi, Samanthi L., Meyer, Christopher J., Lane, Douglas J., Chai, Weirui, Lemmon, Margaret M., Liu, Jiuyu, Butler, Michelle M., Bowlin, Terry L., Lee, Richard E., Panchal, Rekha G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684479/
https://www.ncbi.nlm.nih.gov/pubmed/31164713
http://dx.doi.org/10.1038/s41429-019-0194-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684479/
https://www.ncbi.nlm.nih.gov/pubmed/31164713
http://dx.doi.org/10.1038/s41429-019-0194-8

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