Thermostability as a highly dependent prion strain feature

Prion diseases are caused by the conversion of physiological PrP(C) into the pathogenic misfolded protein PrP(Sc), conferring new properties to PrP(Sc) that vary upon prion strains. In this work, we analyze the thermostability of three prion strains (BSE, RML and 22L) that were heated at 98 °C for 2...

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Detalles Bibliográficos
Autores principales: Marín-Moreno, Alba, Aguilar-Calvo, Patricia, Moudjou, Mohammed, Espinosa, Juan Carlos, Béringue, Vincent, Torres, Juan María
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684573/
https://www.ncbi.nlm.nih.gov/pubmed/31388046
http://dx.doi.org/10.1038/s41598-019-47781-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684573/
https://www.ncbi.nlm.nih.gov/pubmed/31388046
http://dx.doi.org/10.1038/s41598-019-47781-6

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