Mutational processes contributing to the development of multiple myeloma

To gain insight into multiple myeloma (MM) tumorigenesis, we analyzed the mutational signatures in 874 whole-exome and 850 whole-genome data from the CoMMpass Study. We identified that coding and non-coding regions are differentially dominated by distinct single-nucleotide variant (SNV) mutational s...

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Detalles Bibliográficos
Autores principales: Hoang, Phuc H., Cornish, Alex J., Dobbins, Sara E., Kaiser, Martin, Houlston, Richard S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684612/
https://www.ncbi.nlm.nih.gov/pubmed/31387987
http://dx.doi.org/10.1038/s41408-019-0221-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684612/
https://www.ncbi.nlm.nih.gov/pubmed/31387987
http://dx.doi.org/10.1038/s41408-019-0221-9

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