Proteolysis of the low density lipoprotein receptor by bone morphogenetic protein-1 regulates cellular cholesterol uptake

The development of cardiovascular disease is intimately linked to elevated levels of low-density lipoprotein (LDL) cholesterol in the blood. Hepatic LDL receptor (LDLR) levels regulate the amount of plasma LDL. We identified the secreted zinc metalloproteinase, bone morphogenetic protein 1 (BMP1), a...

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Detalles Bibliográficos
Autores principales: Banerjee, Sreemoti, Andrew, Robert J., Duff, Christopher J., Fisher, Kate, Jackson, Carolyn D., Lawrence, Catherine B., Maeda, Nobuyo, Greenspan, Daniel S., Kellett, Katherine A. B., Hooper, Nigel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684651/
https://www.ncbi.nlm.nih.gov/pubmed/31388055
http://dx.doi.org/10.1038/s41598-019-47814-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684651/
https://www.ncbi.nlm.nih.gov/pubmed/31388055
http://dx.doi.org/10.1038/s41598-019-47814-0

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