Genome-wide Phenotypic Profiling Identifies and Categorizes Genes Required for Mycobacterial Low Iron Fitness

Iron is vital for nearly all living organisms, but during infection, not readily available to pathogens. Infectious bacteria therefore depend on specialized mechanisms to survive when iron is limited. These mechanisms make attractive targets for new drugs. Here, by genome-wide phenotypic profiling,...

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Detalles Bibliográficos
Autores principales: Dragset, Marte S., Ioerger, Thomas R., Zhang, Yanjia J., Mærk, Mali, Ginbot, Zekarias, Sacchettini, James C., Flo, Trude H., Rubin, Eric J., Steigedal, Magnus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684656/
https://www.ncbi.nlm.nih.gov/pubmed/31388080
http://dx.doi.org/10.1038/s41598-019-47905-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684656/
https://www.ncbi.nlm.nih.gov/pubmed/31388080
http://dx.doi.org/10.1038/s41598-019-47905-y

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