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Genome-wide Phenotypic Profiling Identifies and Categorizes Genes Required for Mycobacterial Low Iron Fitness
Iron is vital for nearly all living organisms, but during infection, not readily available to pathogens. Infectious bacteria therefore depend on specialized mechanisms to survive when iron is limited. These mechanisms make attractive targets for new drugs. Here, by genome-wide phenotypic profiling,...
Autores principales: | Dragset, Marte S., Ioerger, Thomas R., Zhang, Yanjia J., Mærk, Mali, Ginbot, Zekarias, Sacchettini, James C., Flo, Trude H., Rubin, Eric J., Steigedal, Magnus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684656/ https://www.ncbi.nlm.nih.gov/pubmed/31388080 http://dx.doi.org/10.1038/s41598-019-47905-y |
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