Incomplete influenza A virus genomes occur frequently but are readily complemented during localized viral spread

Segmentation of viral genomes into multiple RNAs creates the potential for replication of incomplete viral genomes (IVGs). Here we use a single-cell approach to quantify influenza A virus IVGs and examine their fitness implications. We find that each segment of influenza A/Panama/2007/99 (H3N2) viru...

Descripción completa

Detalles Bibliográficos
Autores principales: Jacobs, Nathan T., Onuoha, Nina O., Antia, Alice, Steel, John, Antia, Rustom, Lowen, Anice C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684657/
https://www.ncbi.nlm.nih.gov/pubmed/31387995
http://dx.doi.org/10.1038/s41467-019-11428-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684657/
https://www.ncbi.nlm.nih.gov/pubmed/31387995
http://dx.doi.org/10.1038/s41467-019-11428-x

Ejemplares similares