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Evaluation of polydentate picolinic acid chelating ligands and an α-melanocyte-stimulating hormone derivative for targeted alpha therapy using ISOL-produced (225)Ac
BACKGROUND: Actinium-225 ((225)Ac, t(1/2) = 9.9 d) is a promising candidate radionuclide for use in targeted alpha therapy (TAT), though the currently limited global supply has hindered the development of a suitable Ac-chelating ligand and (225)Ac-radiopharmaceuticals towards the clinic. We at TRIUM...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684685/ https://www.ncbi.nlm.nih.gov/pubmed/31659557 http://dx.doi.org/10.1186/s41181-019-0072-5 |