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Isoproterenol-Induced Cardiac Diastolic Dysfunction in Mice: A Systems Genetics Analysis

We examined an isoproterenol heart failure model across a panel of diverse inbred strains of mice, the Hybrid Mouse Diversity Panel (HMDP), using left atrial (LA) and lung weights as well as echocardiogram parameters as surrogates for cardiac diastolic function. We identified gene transcripts that s...

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Detalles Bibliográficos
Autores principales: Wang, Jessica, Huertas-Vazquez, Adriana, Wang, Yibin, Lusis, Aldons J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684968/
https://www.ncbi.nlm.nih.gov/pubmed/31417910
http://dx.doi.org/10.3389/fcvm.2019.00100