Relating evolutionary selection and mutant clonal dynamics in normal epithelia

Cancer develops from mutated cells in normal tissues. Whether somatic mutations alter normal cell dynamics is key to understanding cancer risk and guiding interventions to reduce it. An analysis of the first incomplete moment of size distributions of clones carrying cancer-associated mutations in no...

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Detalles Bibliográficos
Autores principales: Hall, Michael W. J., Jones, Philip H., Hall, Benjamin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2019
Materias:
Life Sciences–Mathematics interface
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685019/
https://www.ncbi.nlm.nih.gov/pubmed/31362624
http://dx.doi.org/10.1098/rsif.2019.0230

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685019/
https://www.ncbi.nlm.nih.gov/pubmed/31362624
http://dx.doi.org/10.1098/rsif.2019.0230

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