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Relating evolutionary selection and mutant clonal dynamics in normal epithelia
Cancer develops from mutated cells in normal tissues. Whether somatic mutations alter normal cell dynamics is key to understanding cancer risk and guiding interventions to reduce it. An analysis of the first incomplete moment of size distributions of clones carrying cancer-associated mutations in no...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685019/ https://www.ncbi.nlm.nih.gov/pubmed/31362624 http://dx.doi.org/10.1098/rsif.2019.0230 |