TERT expression is susceptible to BRAF and ETS-factor inhibition in BRAF(V600E)/TERT promoter double-mutated glioma

The BRAF gene and the TERT promoter are among the most frequently altered genomic loci in low-grade (LGG) and high-grade-glioma (HGG), respectively. The coexistence of BRAF and TERT promoter aberrations characterizes a subset of aggressive glioma. Therefore, we investigated interactions between thos...

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Detalles Bibliográficos
Autores principales: Gabler, Lisa, Lötsch, Daniela, Kirchhofer, Dominik, van Schoonhoven, Sushilla, Schmidt, Hannah M., Mayr, Lisa, Pirker, Christine, Neumayer, Katharina, Dinhof, Carina, Kastler, Lucia, Azizi, Amedeo A., Dorfer, Christian, Czech, Thomas, Haberler, Christine, Peyrl, Andreas, Kumar, Rajiv, Slavc, Irene, Spiegl-Kreinecker, Sabine, Gojo, Johannes, Berger, Walter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685154/
https://www.ncbi.nlm.nih.gov/pubmed/31391125
http://dx.doi.org/10.1186/s40478-019-0775-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685154/
https://www.ncbi.nlm.nih.gov/pubmed/31391125
http://dx.doi.org/10.1186/s40478-019-0775-6

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