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Role of JNK and ERK1/2 MAPK signaling pathway in testicular injury of rats induced by di-N-butyl-phthalate (DBP)

BACKGROUND: Di-N-butyl-phthalate (DBP) is an endocrine disrupting substance. We investigated the adverse effect of DBP on testis of male rat and reveal its potential mechanism of MAPK signaling pathway involved this effect in vivo and in vitro. Gonadal hormone, sperm quality, morphological change an...

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Detalles Bibliográficos
Autores principales: Wang, Hongyan, Zhou, Weipeng, Zhang, Jing, Li, Huan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685163/
https://www.ncbi.nlm.nih.gov/pubmed/31387634
http://dx.doi.org/10.1186/s40659-019-0248-1