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Metabolic engineering for efficient supply of acetyl-CoA from different carbon sources in Escherichia coli

BACKGROUND: Acetyl-CoA is an important metabolic intermediate and serves as an acetylation precursor for the biosynthesis of various value-added acetyl-chemicals. Acetyl-CoA can be produced from glucose, acetate, or fatty acids via metabolic pathways in Escherichia coli. Although glucose is an effic...

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Detalles Bibliográficos
Autores principales: Zhang, Shasha, Yang, Wei, Chen, Hao, Liu, Bo, Lin, Baixue, Tao, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685171/
https://www.ncbi.nlm.nih.gov/pubmed/31387584
http://dx.doi.org/10.1186/s12934-019-1177-y