Transplantation of MHC-mismatched mouse embryonic stem cell-derived thymic epithelial progenitors and MHC-matched bone marrow prevents autoimmune diabetes

BACKGROUND: Type 1 diabetes (T1D) is an autoimmune disease resulting from the destruction of insulin-secreting islet β cells by autoreactive T cells. Non-obese diabetic (NOD) mice are the widely used animal model for human T1D. Autoimmunity in NOD mice is associated with particular major histocompat...

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Detalles Bibliográficos
Autores principales: Su, Min, Lin, Yujun, He, Zhixu, Lai, Laijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685174/
https://www.ncbi.nlm.nih.gov/pubmed/31387620
http://dx.doi.org/10.1186/s13287-019-1347-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685174/
https://www.ncbi.nlm.nih.gov/pubmed/31387620
http://dx.doi.org/10.1186/s13287-019-1347-1

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