Identification of novel antifungal agents: antimicrobial evaluation, SAR, ADME–Tox and molecular docking studies of a series of imidazole derivatives

Thirty-four imidazole-based compounds synthesized by one-pot catalytic method were evaluated for their antifungal and antibacterial activities against several fungal and bacterial strains. None of the compounds had antibacterial activity. Interestingly, compounds 1, 2, 3, 10 and 15 displayed a stron...

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Detalles Bibliográficos
Autores principales: Bouchal, Btissam, Abrigach, Farid, Takfaoui, Abdelilah, Elidrissi Errahhali, Manal, Elidrissi Errahhali, Mounia, Dixneuf, Pierre H., Doucet, Henri, Touzani, Rachid, Bellaoui, Mohammed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685181/
https://www.ncbi.nlm.nih.gov/pubmed/31410411
http://dx.doi.org/10.1186/s13065-019-0623-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685181/
https://www.ncbi.nlm.nih.gov/pubmed/31410411
http://dx.doi.org/10.1186/s13065-019-0623-6

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