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Natural killer T cell activation increases iNOS(+)CD206(-) M1 macrophage and controls the growth of solid tumor

BACKGROUND: NKT cells play an important role in anti-tumor immunity. Alpha-galactosylceramide (α-GalCer), a synthetic glycolipid is presented to natural killer T (NKT) cells by most antigen-presenting cells through CD1d molecules leading to activation of NKT cells. However, the precise mechanisms of...

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Detalles Bibliográficos
Autores principales: Paul, Sourav, Chhatar, Sushanta, Mishra, Amrita, Lal, Girdhari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685184/
https://www.ncbi.nlm.nih.gov/pubmed/31387637
http://dx.doi.org/10.1186/s40425-019-0697-7