Cargando…
Natural killer T cell activation increases iNOS(+)CD206(-) M1 macrophage and controls the growth of solid tumor
BACKGROUND: NKT cells play an important role in anti-tumor immunity. Alpha-galactosylceramide (α-GalCer), a synthetic glycolipid is presented to natural killer T (NKT) cells by most antigen-presenting cells through CD1d molecules leading to activation of NKT cells. However, the precise mechanisms of...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685184/ https://www.ncbi.nlm.nih.gov/pubmed/31387637 http://dx.doi.org/10.1186/s40425-019-0697-7 |