Synthesis, anti-leishmanial and molecular docking study of bis-indole derivatives

We have synthesized new series of bisindole analogs (1–27), characterized by (1)HNMR and HR-EI-MS and evaluated for their anti-leishmanial potential. All compounds showed outstanding inhibitory potential with IC(50) values ranging from 0.7 ± 0.01 to 13.30 ± 0.50 µM respectively when compared with st...

Descripción completa

Detalles Bibliográficos
Autores principales: Taha, Muhammad, Uddin, Imad, Gollapalli, Mohammed, Almandil, Noor Barak, Rahim, Fazal, Farooq, Rai Khalid, Nawaz, Muhammad, Ibrahim, Mohamed, Alqahtani, Mohammed A., Bamarouf, Yasser A., Selvaraj, Manikandan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685257/
https://www.ncbi.nlm.nih.gov/pubmed/31410413
http://dx.doi.org/10.1186/s13065-019-0617-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685257/
https://www.ncbi.nlm.nih.gov/pubmed/31410413
http://dx.doi.org/10.1186/s13065-019-0617-4

Ejemplares similares