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Identification of a pituitary ERα-activated enhancer triggering the expression of Nr5a1, the earliest gonadotrope lineage-specific transcription factor

BACKGROUND: Gonadotrope lineage differentiation is a stepwise process taking place during pituitary development. The early step of gonadotrope lineage specification is characterized by the expression of the Nr5a1 transcription factor, a crucial factor for gonadotrope cell fate determination. Abnorma...

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Detalles Bibliográficos
Autores principales: Pacini, Vincent, Petit, Florence, Querat, Bruno, Laverriere, Jean-Noël, Cohen-Tannoudji, Joëlle, L’hôte, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685283/
https://www.ncbi.nlm.nih.gov/pubmed/31391075
http://dx.doi.org/10.1186/s13072-019-0291-8